European championship holders Spain got their campaign under way on Monday with a 1-0 victory over the Czech Republic.
A Gerard Pique goal late on made sure Vicente Del Bosque's men got off to a winning start as Spain joined Croatia at the top of Group D.
The Republic of Ireland and Sweden predictably shared the spoils in their opener as a Wes Hoolahan goal just after half-time was cancelled out by an own goal from Ciaran Clark.
In the same Group, Italy stunned a highly-fancied Belgian side with strikes by Emanuele Giaccherini and Graziano Pelle to top Group E.
Tuesday saw Hungary take Group F by the scruff of the neck courtesy of a 2-0 triumph against Austria, whilst Cristiano Ronaldo's Portugal found tournament new boys Iceland a tough nut to crack as the game ended 1-1.
Moving to Wednesday, and hosts France booked their place in the last 16 with two goals at the end of the match to see off a brave Albanian team.
Antoine Griezmann steered a header in with just a couple of minutes to spare before that man again, Dimitri Payet popped up to repeat his feat from the opening game.
Earlier, Slovakia defeated Russia 2-1 through a wonder strike from Marek Hamsik, whilst Romania could only draw 1-1 with Switzerland leaving them in a precarious position in Group A.